The main reason you may experience constipation on semaglutide is due to its effect on your digestive tract
Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2. Diabetes, 2012
Gudbergsen H, Overgaard A, Henriksen M, Whrens EE, Bliddal H, Christensen R et al (2021) Liraglutide after diet-induced weight loss for pain and weight control in knee osteoarthritis: a randomized controlled trial
It is frequently recommended by doctors for safe and fast results
Semaglutide does not interact negatively with creatine, caffeine, or other common strength supplements
For acute injuries like recent muscle strains or ligament sprains, 4 to 6 weeks of daily administration followed by 2 to 4 week breaks represents the consensus approach